Mary Allen
Ma ka hoʻohālikelike ʻana i ka genome holoʻokoʻa o nā bitches olakino o ka English Springer Spaniel breed me nā bitches me nā maʻi udder, ua hiki i nā mea noiʻi ke ʻike i nā ʻano ʻano gene i loaʻa i nā ʻīlio me kēia maʻi. Ua like loa ka ma'i ma'i 'opiopio i ka ilio me ka ma'i 'a'ai o ke kanaka. ʻO nā hopena, i paʻi ʻia ma Plos Genetics, ua hana ʻia i loko o kahi papahana e holo ʻia e ke Kulanui ʻo Uppsala a me ke Kulanui ʻepekema ʻo Swedish.
ʻO ka maʻi maʻi kekahi o nā kumu maʻamau o ka make ʻana o nā ʻīlio, a ʻo ka maʻi ʻōpū ʻo ia ke ʻano maʻamau o nā maʻi koko i nā bitches ʻaʻole i neutered. Hoʻopilikia nui ʻia nā bitches waena a ʻelemakule. ʻO nā maʻi koko i hōʻike nui ʻia i kekahi mau ʻano, e like me ka English Springer Spaniel, a no laila hiki ke manaʻo ʻia ʻo nā kumu hoʻoilina ke kōkua i ka loaʻa ʻana o nā ʻīlio.
ʻO kahi pūʻulu noiʻi, ʻo ka hapa nui o lākou e pili ana me ke Kulanui ʻo Uppsala a i ʻole SLU, i kēia manawa ua palapala ʻia nā kumu hoʻoilina ma ka hoʻohālikelike ʻana i ka genome o nā bitches olakino a maʻi o ka English Springer Spaniel breed. Ma kēia ʻano, ua hiki iā lākou ke ʻike i nā genes kahi i ʻokoʻa ai nā ʻīlio i hoʻomohala i nā ʻōpū mai nā mea olakino.
- ʻO kā mākou mau manaʻo kānalua ke kuhikuhi pono ʻia i kahi gene e pili ana i ka mahele cell, CDK5RAP2, wahi a Malin Melin, kekahi o nā mea noiʻi mai ke Kulanui ʻo Uppsala. Loaʻa ia ma kahi o ka chromosome 11 kahi e ʻike ai mākou i nā ʻokoʻa loa ma waena o nā ʻīlio olakino a me nā ʻīlio maʻi.
Hiki i kēia ʻike i ka wā lōʻihi ke alakaʻi i ka hoʻomohala ʻana i kahi maʻi i hoʻomaʻemaʻe ʻia a i ka wā lōʻihi nā lāʻau lapaʻau maikaʻi aʻe. ʻO nā maʻi maʻi maʻi ʻōpio i nā ʻīlio ua like loa me ka maʻi maʻi umauma i loko o ke kanaka a hiki i nā hopena ke alakaʻi i ka ʻike a me nā manawa kūpono no nā wahine me ka maʻi maʻi umauma.
- Manaʻo mākou i kēia manawa e hana ʻia nā haʻawina me nā bitches a me nā wahine, e ʻike i ka hopena o kēia ʻano i ka ulu ʻana o ka maʻi a me ka pane ʻana i ka mālama ʻana i ka maʻi kanesa, wahi a Henrik Rönnberg, kekahi o nā mea noiʻi SLU ma hope o ke aʻo ʻana.
Ma ke Kula Nui o ka ʻEpekema ʻEpekema Suedena (SLU) a me ke Kulanui ʻo Uppsala (UU), ke hoʻomaka nei ka noiʻi koʻikoʻi e pili ana i nā genetics ma hope o nā maʻi ʻīlio. ʻO ke kumu o kēia noiʻi ʻana, ʻo ia ka loaʻa ʻana o ka ʻike e pili ana i ka biology ma hope o nā maʻi hoʻoilina a me ke kākoʻo ʻana i ka hānau ʻana no nā ʻīlio olakino. Hiki ke hoʻohana ʻia ka ʻike no ka hoʻomaikaʻi ʻana i ka lāʻau lapaʻau holoholona a me ka lāʻau kanaka. Hoʻopili ʻia ka noiʻi ʻana i nā maʻi genetic o ka ʻīlio, mai nā ʻano maʻi maʻi like ʻole a i ka maʻi cardiovascular a me nā maʻi ʻaʻa, epilepsy, a me nā maʻi maka.