Mary Allen
He mea maʻamau ka maʻi ʻeha ma nā pōpoki a me nā ʻīlio a hiki ke loaʻa nā hopena koʻikoʻi. E heluhelu maanei i kāu mea e hana ai e kākoʻo i kāu holoholona maʻi maʻi.
Pehea ka ulu ʻana o ka maʻi ʻeha?
Inā hiki i ka hana hoʻopakele i hōʻike ʻia ma luna nei ke hoʻopau i ka pōʻino, pau ka hopena inflammatory acute iā ia iho. Heʻokoʻa kēia ināʻaʻole hiki ke hoʻopau loaʻia ka hopena o ka mumū a iʻole e hoʻonāukiuki pinepine i ka pūnaewele immune. Ua kapa ʻia kēia ʻaʻa maʻi ma muli o ka ʻaʻa nui.
Eia nō naʻe, ʻo ka manawa pinepine ka hoʻomaka ʻana o ka mumū mai ka hoʻomaka ʻana e hoʻomau i ka mālama ʻana iā ia iho i loko o kahi ʻano pōʻai ʻino, e like me ka mea i kapa ʻia ʻo ka maʻi maʻi maʻi mua. ʻO kēia hopena luku lōʻihi, ka mea i nalowale i kona manaʻo physiological, ke kumuhana o ka noiʻi koʻikoʻi no ka mea nona ke kuleana no nā maʻi koʻikoʻi he nui.
He aha nā mea e hoʻolalelale ai i ka ʻā ʻana?
ʻO ke ʻano o ka ʻeha nui, kuhi hewa ʻole, a me ka pau ʻole ʻana he hoʻoilina, no ka mea, ʻo ka maikaʻi a maikaʻi ʻole paha o ka hana ʻana o ka ʻōnaehana immune he hapa genetic. No ka laʻana, ua hoʻoili ʻia ke ʻano o ka maʻi allergies a me nā maʻi autoimmune, akā inā a i ka wā e puka maoli ai lākou e hilinaʻi ʻia i nā kūlana ola.
ʻO ka makahiki, ka meaʻai, ke kaumaha, a me ka pae koʻikoʻi, no ka laʻana, e hoʻoikaika i ka ʻōnaehana immune a pēlā ke ʻano o ka hopena inflammatory, kahi i hoʻonohonoho pono ʻia e nā cell immune. Wahi a ke kūlana o ka noiʻi i kēia manawa, ʻo ka mea i kapa ʻia ʻo ke koʻikoʻi oxidative he kuleana kūikawā.
He aha ka hopena o ka pilikia?
Hoʻomaopopo ʻia ke koʻikoʻi Oxidative ma ke ʻano he keu o nā ʻano oxygen reactive, i kapa ʻia ʻo ROS (reactive oxygen species) - kahi pū kekahi i kapa ʻia nā radical manuahi - a me ko lākou ʻohana, nā ʻano nitrogen reactive, RNS no ka pōkole (reactive nitrogen species).
Hoʻokumu ʻia kēia mau molekele reactive (= oxidants) i loko o ka metabolism cell maʻamau a hoʻopaʻa mau ʻia i loko o nā cell e nā mīkini pale, ʻoi aku ka antioxidants. Eia nō naʻe, inā he ʻokoʻa ma waena o nā antioxidants a me nā oxidants, e hōʻino nā pūhui hoʻopaʻapaʻa, no ka laʻana, nā enzyme metabolic, ka membrane cell, a me ka genetic material (DNA) i loko o ka nucleus cell. Hiki i kēia ke alakaʻi i nā palena hana o ka cell a hiki i ka mutation cancerous a i ʻole ka make ʻana o ka cell i hoʻopilikia ʻia.
ʻO ka oxygen reactive a me nā ʻano nitrogen ke kuleana koʻikoʻi i ka mumū. Hoʻokuʻu ʻia lākou e nā keʻokeʻo keʻokeʻo e pepehi i ka bacteria a i ʻole nā pūnaewele i hoʻopili ʻia, no ka laʻana. Hoʻopili nā RNA i ka dilation o nā kīʻaha koko a hiki ke pepehi ʻia nā cell cancer me ke kōkua o ROS.
ʻO kaʻoiaʻiʻo, he kuleana koʻikoʻi kēia mau mea oxidants i ka pane maʻamau pale inflammatory. Eia nō naʻe, inā ʻaʻole lawa ka mālama ʻia ʻana e nā antioxidants a i ʻole e hoʻomau ʻia ka hana ʻana no ka mea ʻaʻole i kū ka ʻāʻī, wehe pū lākou i kā lākou hopena luku i loko o ka ʻiʻo olakino maoli.
He aha ka hana a ka ʻai a me ke kaumaha?
Hoʻopili ka meaʻai i nā kaʻina inflammatory ma nā ʻano he nui. Ma kekahi ʻaoʻao, pono nā holoholona a me nā kānaka i ka nui o nā meaʻai i hiki i ka ʻōnaehana pale - a me nā ʻōnaehana ʻē aʻe a pau o ke kino - hiki ke hana maʻalahi. No ka laʻana, pono ia i ka ikehu no ka hana ʻana o nā cell immune a me nā poloka kūkulu protein no ka hoʻokumu ʻana i nā mea pale (antibodies) a me nā mea ʻelele (cytokines). ʻO nā antioxidants i ʻai ʻia me ka meaʻai (me nā huaora C a me E) kōkua pū kekahi i ka hakakā pololei ʻana i ke kaumaha oxidative.
Ma ka ʻaoʻao ʻē aʻe, ʻo ka meaʻai i kiʻekiʻe loa i nā calorie e alakaʻi i ka momona a hāpai kēia i nā kaʻina hana inflammatory mau. Mālama ʻia ka ikehu keu i loko o nā pūnaʻi momona, a inā ʻoe i ke kaumaha, hoʻopuka kēia i nā mea messenger pro-inflammatory (cytokines), ka hopena i kahi kūlana inflammatory mau (ka haʻahaʻa haʻahaʻa).
Ua ʻike ʻia mai ka lāʻau lapaʻau kanaka ʻo ka poʻe ma nā ʻāina me ka ʻai nui i nā antioxidants (e ʻike pū i lalo) - no ka laʻana ma ka ʻāina Mediterranean a i ʻole ma India - ʻeha pinepine ʻia i nā maʻi civili pili i ka mumū.