# 10 Enfermidade de Lafora en Beagles
Lafora is an inherited genetic defect responsible for progressive epilepsy. This means that the condition becomes more obvious as one ages. The epileptic seizures also become stronger and occur more frequently. A mutation in the NHLRC1 gene (also called EPM2B) is responsible for neurotoxic inclusions (so-called Lafora bodies) that are stored in the brain and nervous system. However, these inclusions are also found in other organs.
Síntomas de Lafora:
blindness / poor vision
convulsións
tremores musculares
twitching (especially head area)
aggressive behavior/susceptibility to stress
incontinence (as the course progresses)
frequent blinking
demencia
falling over / lying down
trastornos de coordinación
Os estímulos visuais ou auditivos externos (luz intermitente, movemento rápido, ruído forte, etc.) poden desencadear unha convulsión. O beagle permanece plenamente consciente.
Ademais dos síntomas enumerados, que falan da enfermidade de Lafora, unha proba xenética pode xustificar de forma fiable o diagnóstico. Para este fin, examínase unha mostra de sangue con EDTA. Ademais do Beagle, os Dachshunds e os Basset Hounds tamén están afectados pola enfermidade de Lafora. Non obstante, a enfermidade adoita ser máis grave no beagle.
The disease often does not appear until the age of 6 or 7 and can shorten life expectancy. Unfortunately, Lafora cannot be cured. Dogs' quality of life sometimes deteriorates rapidly after the first symptoms appear. Only dogs that have received the mutated gene from both parents become ill. A dog with only one mutated gene remains symptom-free but can pass on the disease.
# 11 Intoxicación: unha emerxencia absoluta
Poisoning can develop very slowly. For example, by ingesting dangerous substances over a longer period of time. This can also be unsuitable food (see beagle nutrition).
Aínda que algunhas toxinas teñen un efecto inmediato, outras teñen un inicio retardado dos síntomas. Este é o caso, por exemplo, do veleno para ratos, que por desgraza tamén se usa con frecuencia cos temidos cebos velenos. Os síntomas de intoxicación poden aparecer incluso días despois da inxestión.
Os seguintes síntomas poden indicar, pero non necesariamente, unha intoxicación. Outras enfermidades tamén son posibles con estes signos. Non obstante, xa que cada segundo conta cando o teu Beagle come algo perigoso, sempre debes consultar inmediatamente a un veterinario se sospeitas de algo. Por certo, moitos síntomas ocorren en combinación.
Sinais de intoxicación:
blood in the feces;
diarrea;
vomitar;
forte salivación;
blood or foam in the vomit;
sangue na orina;
tremer;
under temperature;
calambres;
"cat hump";
narrowed or greatly dilated pupils;
inconsciencia;
circulatory problems (white gums/oral mucosa!);
parálise;
strong restlessness;
very weak condition;
apatía;
problemas respiratorios;
very irregular heartbeat.
But not only poisonous baits pose a danger for the dog. There are many substances in the household that could be dangerous for the beagle. These include, for example, cleaning agents, fertilizers, medicines, cigarettes, alcohol, unsuitable food, and much more.
# 12 Que facer en caso de intoxicación
Keep calm and don't panic.
Leva o can inmediatamente (!) a un hospital de animais ou ao veterinario.
Don't induce vomiting.
Non lle poñas un bucle de fociño ao teu beagle.
Se é posible, colle parte da substancia que se inxeriu/comiu (poña luvas ou colle como feces!)
Collected faeces, urine, or vomit can also provide information about the poison in the veterinary laboratory.
Se é posible, envolve o beagle nunha manta e mantelo quente durante o tránsito.
If the poison was absorbed by the dog via the gastrointestinal tract, charcoal tablets can be administered as a first aid measure (ask the veterinarian about the dosage well before an emergency occurs).