Will Trazodone be harmful to my dog?


Trazodone is a medication that is commonly used in dogs to treat anxiety, insomnia, and other behavioral issues. It works by increasing the levels of serotonin in the brain, which can help to calm dogs down and make them feel more relaxed. Trazodone is available in tablet form, and it is usually given to dogs orally.


The dosage of trazodone that should be given to a dog will depend on the size of the dog, as well as the specific condition being treated. In general, the recommended dosage range is 1.5 to 5 mg per pound of body weight per day. This dosage is typically divided into two or three doses per day. It is important to follow the dosage instructions provided by a veterinarian, as giving too much trazodone can be harmful to a dog.


Trazodone is generally considered to be safe for dogs to take, but it should only be used under the guidance of a veterinarian. Dogs with certain medical conditions, such as liver or kidney disease, may not be able to tolerate trazodone. Additionally, trazodone should not be given to pregnant or nursing dogs, as it can be harmful to developing puppies.

Side effects

Like any medication, trazodone can cause side effects in dogs. Some of the most common side effects include drowsiness, lethargy, vomiting, diarrhea, and loss of appetite. These side effects are usually mild and go away on their own, but in some cases, they may be severe enough to require medical attention.


It is possible for dogs to be allergic to trazodone, although this is rare. Signs of an allergic reaction may include itching, hives, swelling of the face or tongue, and difficulty breathing. If a dog experiences any of these symptoms after taking trazodone, it is important to seek veterinary care immediately.

Medical conditions

Dogs with certain medical conditions may not be able to take trazodone safely. For example, dogs with liver or kidney disease may not be able to metabolize the medication properly, which could lead to toxicity. It is important to discuss any underlying medical conditions with a veterinarian before giving trazodone to a dog.

Drug interactions

Trazodone can interact with other medications, so it is important to inform a veterinarian of any other medications a dog may be taking. Drugs that may interact with trazodone include certain pain medications, antihistamines, and other medications that affect serotonin levels in the brain.


Giving too much trazodone can be harmful to a dog, and it can lead to symptoms such as vomiting, diarrhea, lethargy, and seizures. If a dog has ingested too much trazodone, it is important to seek veterinary care immediately.


If a dog experiences negative side effects from trazodone, it may be necessary to discontinue the medication or adjust the dosage. In some cases, additional treatment may be necessary to manage any symptoms that may arise.


There are other medications and treatments that can be used in place of trazodone to manage behavioral issues in dogs. These may include other prescription medications, as well as natural remedies such as herbal supplements or behavioral training.


Trazodone can be a safe and effective option for managing anxiety and other behavioral issues in dogs, but it should only be used under the guidance of a veterinarian. It is important to follow dosage instructions carefully, monitor for any potential side effects, and seek veterinary care if any issues arise.


Before administering trazodone to a dog, it is important to consult with a veterinarian. A veterinarian can provide guidance on the appropriate dosage, as well as any potential risks or side effects associated with the medication. They can also help to determine if trazodone is the right treatment option for a particular dog, or if other treatments may be more appropriate.

Mary Allen

Written by Mary Allen

Hello, I'm Mary! I've cared for many pet species including dogs, cats, guinea pigs, fish, and bearded dragons. I also have ten pets of my own currently. I've written many topics in this space including how-tos, informational articles, care guides, breed guides, and more.

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