Mary Allen
Los ntawm kev sib piv tag nrho cov genome ntawm kev noj qab haus huv bitches ntawm Askiv Springer Spaniel yug nrog cov bitches nrog udder qog, cov kws tshawb fawb muaj peev xwm txheeb xyuas cov noob variants uas tsuas pom muaj nyob rau hauv cov dev uas muaj tus kab mob no. Cov qog nqaij hlav me hauv cov dev zoo ib yam li tib neeg mob qog noj ntshav mis. Cov txiaj ntsig, uas nyuam qhuav luam tawm hauv Plos Genetics, tau tsim nyob rau hauv ib txoj haujlwm khiav los ntawm Uppsala University thiab Swedish University of Agricultural Sciences.
Mob qog noj ntshav yog ib qho ntawm feem ntau ua rau tuag nyob rau hauv dev, thiab udder qog yog feem ntau cov qog nqaij hlav nyob rau hauv bitches uas tsis tau neutered. Cov hnub nyoog nruab nrab thiab laus dua yog qhov cuam tshuam tshwj xeeb. Cov qog muaj ntau tshaj nyob rau hauv ib co breeds, xws li lus Askiv Springer Spaniel, thiab nws muaj peev xwm yog li ntawd yuav xav tias hereditary ua rau cov dev tau hlav.
Ib pab pawg tshawb fawb, feem ntau yog koom nrog Uppsala University lossis SLU, tam sim no tau piav qhia txog keeb kwm keeb kwm los ntawm kev sib piv cov genome ntawm kev noj qab haus huv thiab mob bitches ntawm Askiv Springer Spaniel yug. Ua li no, lawv muaj peev xwm txheeb xyuas cov noob uas cov dev uas tau tsim cov qog txawv ntawm cov uas noj qab nyob zoo.
- Peb qhov kev tsis txaus siab tshwj xeeb yog qhia txog cov noob uas cuam tshuam rau kev faib cell, CDK5RAP2, hais tias Malin Melin, ib tus kws tshawb fawb los ntawm Uppsala University. Nws pom nyob rau hauv cheeb tsam ntawm chromosome 11 qhov twg peb pom qhov sib txawv ntawm cov dev noj qab nyob zoo thiab mob.
Qhov kev tshawb pom no tuaj yeem ua rau lub sijhawm ntev ua rau kev txhim kho kev kuaj mob kom zoo thiab nyob rau lub sijhawm ntev kev kho kom zoo dua. Cov qog nqaij hlav me me hauv cov dev zoo ib yam li mob qog noj ntshav hauv tib neeg thiab nws muaj peev xwm ua tau tias cov txiaj ntsig tseem tuaj yeem ua rau muaj kev paub zoo dua thiab muaj cib fim rau cov poj niam uas mob qog noj ntshav.
- Peb tam sim no hais tias cov kev tshawb fawb yuav tsum tau ua nrog ob leeg bitches thiab poj niam, saib seb cov noob no cuam tshuam li cas rau kev txhim kho kab mob thiab teb rau kev kho mob qog noj ntshav, hais tias Henrik Rönnberg, ib tug ntawm SLU cov kws tshawb fawb tom qab txoj kev tshawb no.
Ntawm Swedish University of Agricultural Sciences (SLU) thiab Uppsala University (UU), kev tshawb fawb hnyav tab tom ua haujlwm ntawm cov noob caj noob ces qab kab mob dev. Lub hom phiaj ntawm qhov kev tshawb fawb no yog kom tau txais kev paub ntau ntxiv txog biology tom qab cov kab mob sib kis thiab txhawb kev yug me nyuam rau cov dev noj qab haus huv. Kev paub yuav siv tau los txhim kho ob qho tib si kho tsiaj thiab tib neeg cov tshuaj. Cov kev tshawb fawb no suav nrog ntau tus dev cov kab mob caj ces, los ntawm ntau hom mob qog noj ntshav mus rau kab mob plawv thiab kab mob inflammatory, qaug dab peg, thiab kab mob qhov muag.